Nickel-Catalyzed [2+2+2] Cycloaddition of Diynes and Cyanamides
نویسندگان
چکیده
منابع مشابه
Iron-catalyzed cycloaddition reaction of diynes and cyanamides at room temperature.
An iron-catalyzed [2 + 2 + 2] cycloaddition reaction of diynes and cyanamides at room temperature is reported. Highly substituted 2-aminopyridines were obtained in good to excellent yields with high regioselectivity. Insights toward the reaction process were investigated through in situ IR spectra and control experiments. In this iron-catalyzed cycloaddition reaction, the active iron species wa...
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A Ni/N-heterocyclic carbene catalyst couples diynes to the C(α)-C(β) double bond of tropone, a type of reaction that is unprecedented for metal-catalyzed cycloadditions with aromatic tropone. Many different diynes were efficiently coupled to afford [5-6-7] fused tricyclic products, while [5-7-6] fused tricyclic compounds were obtained as minor byproducts in a few cases. The reaction has broad s...
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A transition metal-catalyzed [2 + 2 + 2] cycloaddition between alpha,omega-diynes and 3,4-pyridynes has been realized for the first time, producing isoquinolines in good yields by using a nickel(0) catalyst.
متن کاملRhodium-catalyzed [2+2+2] cycloaddition of oximes and diynes to give pyridines.
Oximes and diynes undergo efficient cycloaddition in the presence of a catalytic amount of a cationic rhodium(I)/dppf complex (see scheme). Spontaneous dehydration of the initially formed cycloadducts leads to the formation of a variety of substituted pyridines in moderate to good yields. The transformation could also be achieved in a one-pot procedure using aldehydes.
متن کاملNickel-catalyzed [4+2] cycloaddition for highly substituted arenes.
Nickel(0) catalyzed [4+2] cycloaddition of electron-deficient dienes to alkynes and subsequent aromatization gave highly substituted arenes. This formal inverse electron-demand Diels-Alder cycloaddition is attributed to the formation of a seven-membered nickelacycle from a diene and an alkyne.
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ژورنال
عنوان ژورنال: European Journal of Organic Chemistry
سال: 2011
ISSN: 1434-193X
DOI: 10.1002/ejoc.201100428